Apoptosis in Mouse Amniotic Epithelium Is Induced by Activated Macrophages Through the TNF Receptor Type 1/TNF Pathway

The Effect of Methanol Extract of Echinops Lasiolepis on TNF-α Production in LPS-activated J774 A.1 Mouse Macrophages

Background and Aims: Plants as medicines have always played a vital role in human life. Tumor necrosis factor alpha (TNF)-α is one of the macrophage-derived inflammatory cytokine with pleotropic effects in the inflammation process. Some studies have been demonstrated that some of the Echinops species have anti-inflammatory activity. In fact, Echinops lasilepis is introduced as one of the ...

Bax is activated during rotavirus-induced apoptosis through the mitochondrial pathway.

Rotaviruses are the leading cause of infantile viral gastroenteritis worldwide. Mature enterocytes of the small intestine infected by rotavirus undergo apoptosis, and their replacement by less differentiated dividing cells probably leads to defective absorptive function of the intestinal epithelium, which, in turn, contributes to osmotic diarrhea and rotavirus pathogenesis. Here we show that in...

Bax is activated during rotavirus - induced apoptosis through the 1 mitochondrial pathway 2 3

19 20 Rotaviruses are the leading cause of infantile viral gastroenteritis worldwide. Mature 21 enterocytes of the small intestine infected by rotavirus undergo apoptosis and their 22 replacement by less differentiated dividing cells probably leads to defective absorptive 23 function of the intestinal epithelium, and this contributes to osmotic diarrhea and rotavirus 24 pathogenesis. 25 Here, w...

PKC is involved in JNK activation that mediates LPS- induced TNF- , which induces apoptosis in macrophages

Comalada, Mònica, Jordi Xaus, Annabel F. Valledor, Carlos López-López, Daniel J. Pennington, and Antonio Celada. PKC is involved in JNK activation that mediates LPS-induced TNF, which induces apoptosis in macrophages. Am J Physiol Cell Physiol 285: C1235–C1245, 2003. First published July 16, 2003; 10.1152/ajpcell.00228.2003.— Lipopolysaccharide (LPS) is a powerful stimulator of macrophages and ...

Regulation of TNF-a Production in Activated Mouse Macrophages by Progesterone